2018年

Hiroyuki Oshiumi

Development of the method to predict adverse reaction caused by vaccination

Kunihiko Nishino

Role of the multidrug efflux pump and its regulation in bacterial homeostasis

THE WAKSMAN FOUNDATION OF JAPAN INC 2018

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2017年

Shinichiro Sawa

Visualization and functional assessment of IL-23 producing dendritic cells in vivo
※論文掲載は2018年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2018」になります。

Tomokazu Fukuda

Establishment of immortalized Bonin flying fox (Pteropus pselaphon) derived cell and it application to the in vitro virus infection model
※論文掲載は2018年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2018」になります。

2016年

Keiko Taguchi

Pathological Analyses in Constitutive Nrf2 Activation in The Liver
※論文掲載は2018年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2018」になります。

Hirofumi Noguchi

The evaluation of reprogramming vectors for the generation of induced tissue-specific stem cells

Yusuke Ohba

Identification and characterization of influenza virus receptor protein

Koki Makabe

Incorporation of VLGDV sequence from αB crystallin into a β-sheet region of outer surface protein A, OspA

THE WAKSMAN FOUNDATION OF JAPAN INC 2016

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2015年

Makoto Akashi

A method for long-term real-time monitoring of gene expression in semi-freely moving mice
※論文掲載は2016年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2016」になります。

Takeshi Yamada:

Analysis of T cell exhaustion observed in tumor suppressor Menin KO mice.

Maho Suzukawa, et al:

Identification of a new marker and its pathogenesis in pulmonary tuberculosis、

Sub title:
Combined analysis of IFN-γ, IL-2, IL-5, IL-10, IL-1RA and MCP-1 in QFT supernatant is useful for distinguishing active tuberculosis from latent infection

Takamasa Ueno, et al:

Relative resistance of HLA-B to down-regulation by naturally occurring HIV-1 Nefsequences

THE WAKSMAN FOUNDATION OF JAPAN INC 2015

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2014年

Shiki Takamura

Autophagy-independent maintenance of resident memory CD8+ T cells in the lung.
※論文掲載は2016年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2016」になります。

Shogo Misumi, et al:

The C-terminal domain of glyceraldehyde 3-phosphate dehydrogenase plays an important role in suppression of tRNALys3 packaging into human immunode?ciency virus type-1 particles
※論文掲載は2015年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2015」になります。

Minoru Andoh, et al.:

Molecular mechanisms for Th17 cell induction by segmented filamentous bacteria (SFB)

Takashi Kawakami:

Discovery of unnatural cyclic peptides from diverse libraries

Tadanobu Takahashi:

Development of novel anti-influenza virus reagent based on binding to asialo-glycochain

Atsushi Nishida:

The role of glycome on immune cells to inflammatory bowel disease

THE WAKSMAN FOUNDATION OF JAPAN INC 2014

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2013年

Masaaki Murakami:

Mechanisms of pathogen invasion into the central nervous system via the inflammation amplifier
※論文掲載は2015年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2015」になります。

Akinori Takaoka:

A novel regulatory mechanism for virus-induced activation of pattern recognition receptors
※論文掲載は2015年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2015」になります。

Hirotaka Kanuka:

Genetic dissection of intermediate host and tapeworm interaction

Jun-ichi Wachino:

Horizontal gene transfer of an amikacin resistant 16S rRNA methyltransferase gene from multidrug resistant Acinetobacter baumannii

Hayato Takahashi, M.D., Ph.D.:

Analysis on the mechanism of T cell peripheral tolerance against pemphigus autoantigen, desmoglein 3

Hitomi Mimuro:

Helicobacter pylori regulate host non-coding RNA expression to increase the proliferation of gastric epithelium during chronic infection

THE WAKSMAN FOUNDATION OF JAPAN INC 2013

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2012年

Minoru Andou et al:

Molecular mechanisms for Th17 cell induction by segmented filamentous bacteria (SFB)
※論文掲載は2014年度版「THE WAKSMAN FOUNDATION OF JAPAN INC 2014」になります。

Masahiro Yamamoto:

Analysis of Toxoplasma gondii-mediated immune evasion and its virulence mechanisms

Hiroki Yoshida, M.D., Ph.D.:

Identification and Characterization of pathogen-derived adjuvant candidate molecules tha activate the CARD9-mediated novel innate immune system

Shigeto Yoshida:

Development of a novel vaccine platform based on non-infectious viral vectors for prevention of malaria

Yasushi Kawaguchi:

Development of novel vaccines againt herpes simplex viruses

Shigeaki Inoue, M.D., Ph.D:

Interleukin 15 increases interferon-gamma production to reverse age-related CD8+ T-cell inactivation and improve survival of aged septic mice

THE WAKSMAN FOUNDATION OF JAPAN INC 2012

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2011年

Yasuhiko Horiguchi:

Study on the mechanism causing paroxysmal cough in whooping cough

Hiroaki Takatori:

The Role of Lymphoid Tissue Inducer-like Cells in Chronic Antigen-induced Airway Inflammation

Norihiko Watanabe:

Immune mechanisms involved in the development of fatal autoimmune hepatitis in mice

Haruhiko Suzuki:

Application of CD8+ regulatory T cells to Inflammatory Bowel Disease

Hidekazu Kuwayama:

Analysis of activation pathway of Huntington’s disease-causing gene in Dictyostelium discoideum

Yukihiko Aramaki:

Induction of regulatory T cells following intranasal administration of liposomes composed of phosphatidylserine

THE WAKSMAN FOUNDATION OF JAPAN INC 2011

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2010年

Naoto Ishii:

A novel mechanism for the generation and maintenance of memory T cells

Kunihiko Nishino:

Role of small RNA in regulation of bacterial multidrug resistance

Tomohiko Tamura, et al.

Aberrant differentiation of dendritic cells in malaria infection

Michinaga Ogawa:

Listeria monocytogenes ActA-mediated escape from autophagic recognition

Zhe Wang, et al.

APOBEC3 deaminates the E2 gene of human papillomavirus-16

Kunikazu Moribe:

Preparation of amphotericin B nanoparticles for deep mycosis and the formulation optimization based on physicochemical and biodistributional characterization

Tsukasa Seya:

The Natural killer cell activation by Pam2 lipopeptides in vitro and in vivo

THE WAKSMAN FOUNDATION OF JAPAN INC 2010

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2009年

Kuniyasu Ochiai

Effects of butyric acid, metabolic by-products of anaerobic bacteria, on microbial interaction.

Masahiro Eguchi

Analysis of immune response via TLR4 expression cell in Pertussis infection.

Akira Ishiko, MD, PhD

Analysis of ultrastructural localization of the pathogenic epitope in pemphigus foliaceus

Shogo Kikuchi, et al.

Analysis of infection route for Helicobacter pylori in Japanese children

Ikuo Kawamura

Contribution of the PD-1/PD-L1 pathway to the survival of Mycobacterium bovis BCG in mice

Ryutaro Kamijo, et al.

Involvement of transcription factor IRF-8 in bone metastasis of cancer

THE WAKSMAN FOUNDATION OF JAPAN INC 2009

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2008年

Kazuhiro Kogure

Phylogenetic analyses of marine Pseudomonas

Haruhiko Taguchi

Establishment of mycoplasmal pneumonia model using germ-free mice

Akira Nishizono

Evaluation of a new tumor necrosis factor-a-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen

Yimin

Negative interaction between interleukin-10 and interlekin-6 in mice infected with Rhodococcus aurantiacus

Akiko Takaya

Trafficking of Salmonella virulence factors in host cells

Koichi Kubota

Studies on the innate lymphocyte recognition of macrophage cell death induced by bacteria

THE WAKSMAN FOUNDATION OF JAPAN INC 2008

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2007年

Hiroshi Kiyono

New Horizon in the Development of M Cell Targeted Oral Vaccine for the Induction of Toxin Neutralizing Antibody Response

Hiroyuki Yamaguchi

Role of free-living amoeba as a reservoir for survival of Helicobacter pylori in natural environment.

Masatoshi Noda

Study on the receptor of enterohemorrhagic Escherichia coli SubAB toxin and its cytotoxicity

Toshihiko Suzuki

The Role of Nod-like Receptor Family Member proteins on Caspase-1 Activation in Shigella-infected Macrophages

Akio Nakane

Study on Multi-functions of Staphylococcal Enterotoxin

Yasuo Ohnishi

Global analysis of secondary metabolism in Streptomyces griseus using genome information

Jiro Nakayama

Screening of inhibitors targeting cyclic peptide-mediated quorum sensing in gram-positive bacteria

Tsutomu Hohdatsu

Analysis of the mechanism of antibody-dependent enhancement of feline infectious peritonitis virus infection: Necessity of virus receptors, elucidation of the route of cellular invasion by viruses, and influence of serotype difference

Hidekazu Suzuki et al.

Rapid assessment of fluoroquinolone resistance of H. pylori and the development of third-line erdication therapy

Koichiro Ohmura

Association of HLA-DRB1 with anti-citrullinated peptide antibody production in the Japanese rheumatoid arthritis patients.

THE WAKSMAN FOUNDATION OF JAPAN INC 2007

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2006年

Eijiro Adachi

Restoration to a Contractile Phenotype from Dedifferentiated Status of Smooth Muscle Cells in Double Layered Vascular Constructs

Toshiya Hirayama

Study on the receptor of Helicobacter pylori VacA and its p38MAPK activation

Shigenori Nagai

The Role of PI3K on Cytokine Production by Plasmacytoid Dendritic Cells

Takeo Usui

Establishment of the system for drug target estimation by proteomic approach

Kazuyuki Ishihara

Molecular analysis of colonization and tissue penetration of Treponema denticola

Yukio Koide

Intratracheal administration of the third-generation lentivirus vector encoding Mycobacterium tuberculosis induces specific T-cell responses in the lung

THE WAKSMAN FOUNDATION OF JAPAN INC 2006

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2005年

Haruo Ikeda

Chromosome Engineering for Efficient Production of Secondary Metabolitesin Streptomyces

Masaaki Iwanaga

Fluctuation of Drug Susceptibility of Vibrio cholerae O1 and Analysis of the DrugResistance Genes

Keizo Yamaguchi

Development of Novel Approach for Treatment of Infectious Diseases Targeting Bacterial Cell-to-Cell Signaling: Focusing on an Opportunistic Pathogen Pseudomonas aeruginosa

Tetsuo Kato

Effects of Synthetic N-Acyl Homoserine Lactones and Eel Lectin on Oral Pathogens

Hidero Kitasato

Role of Prostaglandin D2 in Remodeling of Pulmonary Artery Affected by Pulmonary Hypertension

Susumu Ishida

Immunotherapy Targeting VEGFR-2 for Prevention from Pathological Retinal Angiogenesis

THE WAKSMAN FOUNDATION OF JAPAN INC 2005

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2004年

Kozo Ochi

Genetics and Physiology of Ribosomal Mutations That Activate Antibiotic Production; Further Development of Ribosome Engineering

Nobutaka Funa

Type Ⅲ Polyketide Synthases Responsible for Phenolic Lipids Synthesis in Azotobacter vinelandii

Fuminobu Yoshimura

Major Outer Membrane Proteins Homologous to OmpA in Porphyromonas gingivalis

Masashi Emoto

Mechanism of Generation of NK1.1－Va14＋NKT cells in the Liver of Listeria monocytogenes Infected Mice and Possible of These Cells in Protection from the Infection

Yoshimasa Yamamoto

Immune Response of lymphocytes infected with Chlamydia pneumoniae

Tsutomu Takeuchi

Aberrant Signal transduction through T cell Antigen Receptor and Its Correction in Patients with Systemic Lupus erythematosus

Research by Recipient of the Grant for Sending

Scientist Abroad to Study

Mitsuaki Nishibuchi

Study on the Prediction and Prevention of Cholera Epidemic among the Children in Bangladesh

THE WAKSMAN FOUNDATION OF JAPAN INC 2004

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2003年

Hiroyasu Onaka

Studies on Goadsporin : Mechanism of Its Action on the Induction of SecondaryMetabolism and Sporulation in Streptomycetes, and Its Application

Yutaka Sato

A Novel 120kDa Wall-Anchored Protein Produced by Oral Streptococcus mutan

Hisaaki Sato

Analysis of Target Protein of Staphylococcus hyicus Exfoliative Toxins (SHETs)

Koichi Matsuo

Roles of Transcription Factor c-Fos in Response to Bacterial Infection

Hiroshi Kawasaki

Comparison between Antigen-Presenting Activities of Dendritic Cells and those of Langerhans Cells, and Activation of T Cells by Antigen Trans-loaded from Langerhans Cells to Dendritic Cells

Yoshinobu Kimura

Activation of JNK/SAPK and p38 MAPK Signal Transduction Pathways in the MouseBrain upon Infection with Neuroviruleut Influenza A Virus

THE WAKSMAN FOUNDATION OF JAPAN INC 2003

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2002年

Kenji Ueda

Studies on the function and role of AmfS, a peptidic signal that regulates the onset of streptomycin production and morphological differentiation in Streptomyces griseus

Keiji Oguma

Establishment of a new procedure for purifying fully activated Clostridium botulinum type B neurotoxin for treatment of patients with dystonia

Akio Abe

Supramolecular strauture of the Enteropathogenic Escherichia coli type Ⅲ secretion system

Toshiaki Ohteki

Distinct sets of IL-15 producing cells are required for memory CD8+T,NKT,NKand intraepithelial T cell

Minoru Sasaki

Involvement of Streptococcus anginosus infection in oral cancer

Katsuji Okuda

Invasion by periodontopathic Treponema denticola into the circulation and vascular endothelium

2001年

Shohei Sakuda

Studies on a Physiological Role of the Chitinase Inhibitor, Allosamidin, in Allosamidin-Producing Streptomyces.

Tomoko Yamamoto

Studies on Molecular Mechanism of Salmonella Infection by Proteomics

Yutaka Hattori

Efficient Expansion of K-sam Gene-Transduced Hematopoietic Stem Cells by Stimulation with Keratinocyte Growth Factor; A Novel Approach towards Stem Cell Transplantation Therapy

Fumiya Obata

Characterization of T-cells Mediating Chronic Rejection of Kidney Allografts

Motohide Shimazu

A Novel Strategy Using Intra-portal Infusion Therapy in Liver Transplantation across ABO Blood Group Barriers

Appendix

Keizo Yamaguchi

Report on The Ttavel Grant for Young Scientists Who Attend International Scientific Meeting:“The 5th Medical Microbiology Interdisciplinary Committee (MEMIC) Symposium”

2000年

Tadashi Wada

Cell differentiation and transcription elongation reaction

Tsuneyo Mimori

Studies on clinical and pathogenic significance of autoantibodies to　calpastatin in patients with rheumatoid arthritis

Katsuya Gomi

Isolation of transposons from aspergillus oryzae and theirapplication for efficient insertional mutagenesis

Nobuhiko Okada

Functional role of Spv ptoteins,the plasmid-encoded virulence factors that required for systemic infections by Salmonella

Shinichi Nakamura

Regulatoty molecules involved in toxin production by Clostridium difficile